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Showing posts with the label Hematology

COVID-19: Routine hematology parameters play a significant role in diagnosis

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It is interesting to know how a routine blood test can give the clinician a plethora of information! Pathologists the world over are relying on various hematology parameters for severity assessment of COVID-19. Renowned scientific and clinical publications have now concluded that various biochemistry and hematology parameters play an essential role in the early detection, prognosis and management of COVID-19. Significant reduction in absolute Lymphocyte count and Hemoglobin, is associated with the increase in total WBC count, absolute Neutrophil count, ESR, Prothrombin Time, D-Dimer, C-Reactive Protein and Pro-calcitonin. Additionally, various routine biochemical parameters also get deranged and signify the severity and poor prognosis. These lab findings, especially elevated Ferritin levels, suggest an imminent ‘Cytokine Storm’ which might lead to complications like Acute Respiratory Distress Syndrome (ARDS), Pneumonia and Multi-organ Failure (MOD). Elevated troponins & CK-MB signi...

Early diagnosis is critical to containing the growing number of Sickle cell disease cases in India

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Did you know the prevalence of Sickle Cell Anemia in India is the second largest worldwide? On the occasion of World Sickle Cell Awareness Day, we give you an insight into this hereditary disorder that is a growing concern for the country. Rahul, a six year old, from a remote area in Chattisgarh, often misses school.+ Vikram a young, 22 year old boy from Gujarat recently grabbed a lucrative offer at one of the MNCs. However, he had to soon quit. + Rahul and Vikram are both related, not by blood, but by a blood disorder - Sickle Cell Disease. A group of inherited disorders affecting the hemoglobin, sickle cell disease, can cause severe and life-threatening consequences, such as anemia, infections, stroke, tissue damage, organ failure, intense painful episodes and premature death. A chronic disorder of global health importance, ironically, sickle cell disease, is often neglected. India is estimated to have the second highest burden of the disease in the world, a fa...

Affordable hematology testing is the need of the hour

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A blood test today holds the key to every treatment outcome. In the wake of the growing number of blood disorders, hematology testing has become critical. In order to reach out to the 70% Indians in need of blood testing, manufacturers need to provide solutions that are affordable and give accurate results. The increasing prevalence of blood diseases and disorders, pose a global health challenge and are associated with high morbidity and mortality. From the patients’ perspective, this has led to increasing awareness of diseases and shift from sickness to wellness. Look at it from the perspective of the IVD Industry; hematology has grown to be recognized as a distinct steam of laboratory medicine. Technological advancements, increasing adoption of automated hematology instruments, integration of basic flow-cytometry techniques, usage of microfluidics technology, introduction of digital imaging for cell morphology, rising demand for high-throughput hematology analyzers &...